[Hplusroadmap] Fwd: [ExI] Bootstrapping a singularity (not-essay) (was Re: MAX MORE in Second Life yesterday)

[Bryan Bishop]

On Saturday 14 June 2008, Jim Hardy wrote:
> I've done plenty of culturing tissue slices.  The primary obstacle to
> overcome is the short life in vitro due to inconsistent permeation of
> the culture medium into the deeper cells of the tissue vs. the
> peripheral cells. There are a couple ways to get around this, like
> some of the work being done with hollow fiber bioreactors, although
> they are not perfect either.

So, for the depth and volume issues, I think that's why some (or is it 
just me?) propose the slicing idea where you sheet up single-layer or 
very few layer tissue slides (2D cell arrays) and then allow diffusion 
over the tops and bottoms of the sheet. However, this isn't the same 
thing as growing the full system itself, i.e. it's cheating the 
vascularization problem and the stem cell research that would 
undoubtedly be involved. Hollow fiber scaffolds sound interesting, how 
does it work? Is it a pre-layered scaffolding system?

- Bryan
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http://heybryan.org/