[Hplusroadmap] Fwd: [ExI] Bootstrapping a singularity (not-essay) (was Re: MAX MORE in Second Life yesterday)

[Jim Hardy]

Womack and Jones teaches you how to actually make things.  Deming teaches
you that you must manage the entire system of transforming raw materials
into a "part".  Parts is parts, whether they be biological parts or nuts &
bolts.  That's a tough pill for people in life science to swallow, I know.

Maybe Shigeo Shingo is a bit more hand-on, though.

I've done plenty of culturing tissue slices.  The primary obstacle to
overcome is the short life in vitro due to inconsistent permeation of the
culture medium into the deeper cells of the tissue vs. the peripheral cells.
There are a couple ways to get around this, like some of the work being done
with hollow fiber bioreactors, although they are not perfect either. 

-----Original Message-----
From: hplusroadmap-bounces at heybryan.org
[mailto:hplusroadmap-bounces at heybryan.org] On Behalf Of Bryan Bishop
Sent: Saturday, June 14, 2008 11:10 AM
To: Transhumanist Technical Roadmap
Subject: Re: [Hplusroadmap] Fwd: [ExI] Bootstrapping a singularity
(not-essay) (was Re: MAX MORE in Second Life yesterday)

On Friday 13 June 2008, Jim Hardy wrote:
> Point #1:  Look for Womack & Jones:  "Lean Thinking" and "The Machine
> that Changed the World.  These are good books, and they strive for
> perfection. Also, any book by W. Edwards Deming
> [http://en.wikipedia.org/wiki/W._Edwards_Deming] is amazing.

Looked at them yesterday. It looks like they are more 
management-oriented, rather than presenting how the processes are made 
and how to actually get the products and materials you need to get 
things rolling. Maybe this is just a catalogging issue. Anyway, I also 
found Kalpakjian who has apparently written some good texts.

> environmental inputs. Learned behavior, in a sense.  The human body
> is still the most sophisticated computer known to mankind.  The only
> system we know of (which is being quite silly because any mammal is
> in the fold), which continuously monitors their environment at
> changes that environment to be more favorable towards their
> sustenance.  We are a long ways from understanding how to build a
> computer that can do this.  We first need to understand how we are
> able to do it.

Actually, although it's exciting to imagine computers doing similar 
things, like Markram's giant brain simulatons or the recent Palo Alto 
visual cortex simulations that were announced on Slashdot as of 
yesterday, I've been collecting notes on how to go about setting up 
organotypical slice cultures and neurotissue cultures and the like, the 
concept of a 'brain farm' and such. Since the brain works (when it 
wants to) I don't see why implementing them is so terrible.

http://heybryan.org/mediawiki/index.php/Neurofarm

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