[Hplusroadmap] Fwd: [BBF Standards] Input/output

[Dan Bolser]

You might want to study a simple system first. The slime mould
Dictyostelid have an interesting communication protocol based on cAMP
- which is a very common 'secondary messenger' in cellular systems.

http://en.wikipedia.org/wiki/Dictyosteliida


Similarly, methods of neuronal communication should be interesting to
study. I heard about a new kind of chip that supported a live cell
culture of rat brain. The researchers could 'talk to' the brain cells
via electrodes implanted on the chip. This stimulus was used to track
how brain cell development was related to information processing.
However, one could imagine lots of other nice ideas based on the
'brain chip'.




On 11/02/2008, Bryan Bishop <kanzure at gmail.com> wrote:
>
> A few more thoughts --
>
> A relevant input/output system will be much like one for a highly
> parallel complex system. I imagine it would be something like
> MapReduce/Hadoop except for taking apart massive communication
> protocols as well as factory production routines and splitting up the
> tasks into multiple components. This sort of programming language would
> be easily portable to MNT or bacteria (given a genetic interface).
>
> - Bryan
>
> ----------  Forwarded Message  ----------
>
> Subject: [BBF Standards] Input/output
> Date: Monday 11 February 2008
> From: Bryan Bishop <kanzure at gmail.com>
> To: standards at biobricks.org
>
> I was talking with a Slashdot user yesterday who reminded me one of the
> important points that I have been missing when it comes to biobricks,
> namely the goal of data i/o, and so I have briefly outlined an idea for
> a standard and am hoping the list can add a few thoughts to this:
>
> Radioprotein:
> * Protein antenna
> * For starters - chemical substrate to activate enzyme.
> ** Later: integral protein / receptor site. Ex: catch 1% of dopamine.
> * Evolutionary experiments with relevant selector?
> ** those colonies which are able to transmit are triangulated are given
> food by a mechanical arm in a few tanks?
> A first project: radio-controlled bacterial movement.
>
> The problem is that there is never going to be just _one_ radioprotien
> and there's no way that we are going to be hacking together a single
> bit transmission system. Instead, we are going to be getting tons of
> bits and bytes out of bacterial colonies at the same time, in parallel,
> and need a way to record this information. Unfortunately, from what
> little I know of protein expression, this seems to mean that it will
> always involve molecular gradients for comm, and we are not all that
> good at working with molecular gradients. Perhaps we have to study the
> genetics of the cellular messenging systems? I hope it's a template.
>
> - Bryan
>
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