[Hplusroadmap] DNA replication visualization

[Dan Bolser]

Sounds good :-)

On 08/02/2008, Bryan Bishop <kanzure at gmail.com> wrote:
> On Friday 08 February 2008, Dan Bolser wrote:
> > One general comment about the wiki is that I think we should not try
> > to compete with wikipedia. The most important thing is the road map
>
> It most certainly should not compete with Wikipedia or any other general
> resource out there. But caching a few documents is fine -- I have been
> trying to add the topic within a certain point of view, that of
> biohacking, though have some more revisions to go through because of my
> lack of knowledge on the subjects.
>
> > and topics directly linked to it that are specific to the central
> > topic of the project (biohacking).
>
> For the biohacking subset, I saw a neat video last night with Drew Endy:
>
> 1) Genetic engineering stuff
> -- 1.1) PCR (DNA amplification) (fairly simple)
> -- 1.2) Oligonucleotides (DNA synthesis - see 1989 review, next zip)
> -- 1.3) Sequencing (see $0 genome project)
> 2) Synbio stuff
> -- 2.1) Automated oligonucleotide synthesis (see POSAM[1])
> -- 2.2) Standards
> -- 2.3) Abstraction
>
> The purposes of the biokit seem to squarely fall under #1 and #2.1.
> Ideally, we can provide enough information so that enthusiasts can do
> practical PCR runs, can synthesize oligonucleotides from scratch if
> they had to (or order from somebody else), and do sequencing as well,
> all while maintaining good cultures and safety. Then, the next part of
> the toolset is the automated DNA synthesizer -- there is already an
> open source project out there, but it seems to reside anonymously,
> perhaps we can work on writing some information as to how to build or
> use it, etc.
>
> And as for the broader purposes of the roadmap, perhaps I can throw in a
> few pages here and there. But otherwise I think Sourceforge strongly
> frowns on such coupling practices. I'll double check. I am long overdue
> to describe more about the roadmap, so if anybody wants to bring up
> questions regarding it, that would be great.
>
> > We should not get distracted writing articles on basic biology when
> > perfectly good stuff abounds on the internet.
>
> I agree. But putting it into perspective, even if this means one or two
> sentences after an external link, is very helpful.
>
> - Bryan
>
> [1] http://www.bioinformatics.org/pogo/
> ________________________________________
> Bryan Bishop
> http://heybryan.org/
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