Are you looking for the open source do-it-yourself synthetic biology toolkit? It's a small (but ambitious) component of an even larger project, the metarepository (or "autogenix") project.

Metarepository project


What was originally 'only' an an attempt at bruteforcing the design of macroscale kinematic self-replicating machines has now grown into a broader project that is uniting the paired visions of an open knowledge (recipe) database/repository (OSCOMAK, OSEP, SKDB, etc.) with the vision of automated crawling of massive material databases geared towards finding designs that represent self-replication. This metarepository project provides an aggregation framework to physically "ground" the semantic web to reality, such as through physical fabricational recipes -- a "matter compiler" with humble origins as xxDNA; ultimately this is a global, distributed, asynchronous repository paired with fabricational automation (as in real machines -- robotic arms, lathes, general instrumentation) that provides, in a sense, a 'cybernetic circuit' to pull all of our combined "virtual efforts" together, down-to-earth, for increasingly real work -- indeed, discovering the future by creating it. Examples of potential projects within this metarepo would include debian (review), vehicles, wafers, in vitro meat pods, spaceships, DNA synthesizers, etc. Technically, the underlying framework is git + ikiwiki + agx-get + ATLAS-L architecture re: knowledge nugget (knugget) producers, brokers, and users as described by jer -- much of this architecture is already in place with such technologies as YAML, python, HTTP, essentially the entire work done by GNU and the subsequent linux distribution communities. Simultaneously, bottom-up diffusion is pointing this direction as it is. The implementation is not a matter of difficulty but rather a matter of aggregating the combined efforts of programmers, scientists, engineers, etc. All of the puzzle pieces are already out there and are generally well understood. The implications of a distributed, computationally organized and voluntary manufacturing community go beyond scarcity-centric economics and into the development of self-replicating technologies (a strategy to make RepRap actually do what it's supposed to do (replicate)); theoretically, programmable self-replicating machines mean exponential growth that, if indeed open and free, will be our bridge from an age of scarcity economics to an era of post-scarcity, an open singularity. All that's left is crossing the bridge, uniting 'physical' and 'virtual' in both computational and fabricational recursion.

Critics complain civilization is too big, too dense, overpolluted, overpopulated, too smelly, too inhuman, etc. As any good programmer knows, there are times when to rewrite programs from the ground up and times to go about "debugging society". By no means has society 'failed' but this doesn't mean there isn't any room left for optimization, for having fun and exploring new niches and new ways of doing things. Debugging society means tracking down functions, processes, variables, the 'genealogy' of it all and then doing (sandboxed) experimentation to see what we can come up with due to the new 'literacy' of Gershenfeld (below).

What is post-scarcity? According to Wikipedia:
Post scarcity or post-scarcity describes a hypothetical form of economy or society, often explored in science fiction, in which things such as goods, services and information are free, or practically free. This would be due to an abundance of fundamental resources (matter, energy and intelligence), in conjunction with sophisticated automated systems capable of converting raw materials into finished goods, allowing manufacturing to be as easy as duplicating software.
This is not a utopian vision. Raw materials must always be used -- but not necessarily money. There is no free lunch, but not when you start talking about money -- this is because physical possibility is not dictated by money (but perhaps instead by limits to creativity ;-)). It is important to realize that money is our tool for essentially ration unit tokens within an arbitrary societal framework for doling out resources out of perceived scarcity. As for manufacturing to be as easy as duplicating software, automated manufacturing, in today's civilization, is based off of tech that has schematics. These schematics are digital - the tech is creating itself, this is about harnessing that, perhaps one day to make a von Neumann probe or astrochicken. But is it possible? Are self-replicating machines possible? The past four billion years of biology say yes, absolutely, cells and DNA are the units of life itself. But biology is not enough. You have to do amorphous fabrication with cells, and translating human thoughts into parallel executable code is not something that humans are trained to do -- we think linearly, we write line by line; the amorphous computation problem is being extensively studied, however, and indeed is something that should not be ignored (see synthetic biology, biohack, diybio, biopunk, oww, bbf/parts, etc.). You'd need to work on amorphous compilers. So, while the biobrick registry could be included in metarepo, other projects towards solid state self-replication would also be implicated, even those that don't seem to be "on topic" such as electric-arc welding, or methods of making a hot cup of coffee.

From this combination of passion and inventiveness I began to get a sense that what these students are really doing is reinventing literacy. Literacy in the modern sense emerged in the Renaissance as mastery of the liberal arts. This is liberal in the sense of liberation, not politically liberal. The trivium and the quadrivium represented the available means of expression. Since then we've boiled that down to just reading and writing, but the means have changed quite a bit since the Renaissance. In a very real sense post-digital literacy now includes 3D machining and microcontroller programming. I've even been taking my twins, now 6, in to use MIT's workshops; they talk about going to MIT to make things they think of rather than going to a toy store to buy what someone else has designed. The World Bank is trying to close the digital divide by bringing IT to the masses. The message coming back for the fab labs is that rather than IT for the masses the real story is IT development for the masses. Rather than the digital divide, the real story is that there's a fabrication and an instrumentation divide. Computing for the rest of the world only secondarily means browsing the Web; it demands rich means of input and output to interface computing to their worlds. There was an amazing moment as I was talking to these Army generals about how the most profound implication of emerging technology for them might not lie in designing a better weapon to win a war, but rather in giving more people something else to do. So we're now at a cusp where personal fabrication is poised to reinvent literacy in the developed world, and to engage the intellectual capacity of the rest of the world.
-- Neil Gershenfeld


One of the subprojects involves the open source biotech toolkit as a way to more formally make progress even in the lack of philanthropism needed to get the instrumentation up and running. As part of the do-it-yourself biotech toolkit, being developed is a "bioreactor". The setup is being designed to be completely self-replicable including all necessary molecules and materials needed to reprogram DNA and other components of life. At the moment work is being done on biological in vitro DNA synthesizers [but hopefully in vivo]. This would allow individuals to work with cell cultures, purification setups, gels and other tools that can help fight diseases, aging, death, and biological componentry gone wrong -- even perhaps towards enhancement in the traditional transhuman sense.


The basic idea of a von Neumann probe is to have a space-probe that is able to navigate the galaxy and use self-replication (see RepRap and bio). The probe would contain hundreds of thousands of digital genomes (sequenced DNA), DNA synthesizers and sequencers, bacteria, embryos, stem cells, copies of the Internet Archive and a significant portion of the WWW in general, plus the immediate means and tools to copy all of the information and create a material embodiment, kind of like running an unzip utility on top of the thousands of exabytes predicted to be inexistence today. This would probably include many people, societies, even entire civilizations if we can collect enough data and begin to 'debug' civilization. The system might end up using an ion drive and a hydrogen collector, with on-board nucleosynthesis to create the biomolecules necessary for life, plus ways to attach to asteroids and begin replicating and copying the data and biomaterials.

Self-replication is, in general, an interesting problem. See the Center for Bits and Atoms, RepRap, some MNT websites, etc. In debates and discussions in wta-talk and extropy-chat, there has been many a suggestion that mastery of self-replication will lead to post-scarcity economics or acceleration in some way-shape-or-form. The three methods mentioned on this page are (1) atom holography (generally: precision control of matter/energy), (2) molecular nanotechnology (MNT), and (3) bacterial bootstrapping (with the open source synbio/biohacking community, biobricks, the synbio mailing list, Church, Reese, Endy, ...), though RepRap might get to it first with the 3D fabricators. An often unexplored and unmentioned method is semiconductor manufacturing but a good first step would be a si-fab that can make a fab on a chip. An alternative might be graphene etching with AFM nanolithography ($100 AFM/STM setups).




Please contact Bryan if you have any questions while this document is in preparation. The TODO at the moment is basically to work on agx-get and see if the debtorrents project is interested in integration re: metarepo architecture/infrastructure. Ben Lipkowitz is working on autospec, and agx-make/cupsd is the component to make 'build jobs' for some manufacturing environment. See skdb and getting up to speed and maybe the roadmap.


Eric Hunting on the manufacturing ecology
Bryan Bishop on spacetech & manufacturing re: space habitats, NSS, ISDC2008
The Marginalization of Scarcity (Robert Levin)
A rant on financial obesity, Paul Fernhout
On funding post-scarcity digital public works, Paul Fernhout
A post to blenderartists.org re: the repository project and blender models
Narya Forum and Project Incubator
Network for Open Science Innovation
Virtual Manufacturing Initiative
(defunct) NIST Manufacturing Engineering Toolkit (METK)
   [ps] Overview of the Manufacturing Engineering Toolkit Prototype (Michael J. Iuliano, 1995)



I'd suggest relabeling "singularity" before you look for serious money. What you are really talking about is breaking the one brain one lifespan limit to the growth of intelligence.
-- Tony Smith
... which still has to be incorporated into this document.

Here's a video on the toolkit.